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Claude 设计蝎毒蛋白结合体,211 个方案中 17 个通过结合测试

Claude 在与 Citrini Research 合作制定的提示下设计蝎毒蛋白结合体;Adaptyv Bio 和 Twist Bioscience 对 211 个方案进行了实验测试,其中 17 个符合结合体标准。团队已公开全部设计及数据,但尚未验证这些结合体能否在细胞环境中中和蝎毒,不能称其为抗毒血清。

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Claude designs scorpion toxin binders; 17 of 211 designs meet binding criteria

Claude designed protein binders against scorpion neurotoxins using prompts developed with Citrini Research. Adaptyv Bio and Twist Bioscience experimentally tested 211 designs, 17 of which met the team's criteria for a binder. The team has released all designs and data, but has not confirmed whether the binders neutralize venom in cells and does not claim to have produced an antivenom.

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Rohan Paul (@rohanpaul_ai) 同事件 机器翻译
编辑优先级 54/100
Claude designs scorpion-toxin-binding proteins; 17 of 211 tested designs bind

In Anthropic’s Claude Science setup, Claude selected toxin targets, directed 12 protein-design programs, and chose 180 of 318,484 generated molecules for physical synthesis. The source reports that 17 of 211 designs tested at Adaptyv Bio and Twist Bioscience bound their target toxins. Anthropic is not calling the result an antivenom because the test needed to justify that term has not yet been run.

另有 1 家信源报道Anthropic 研究成果 同一事件,精选展示《Claude 设计蝎毒蛋白结合体,211 个方案中 17 个通过结合测试》
Anthropic 研究成果 精选 机器翻译
编辑优先级 68/100
Claude designs scorpion toxin binders; 17 of 211 designs meet binding criteria

Claude designed protein binders against scorpion neurotoxins using prompts developed with Citrini Research. Adaptyv Bio and Twist Bioscience experimentally tested 211 designs, 17 of which met the team's criteria for a binder. The team has released all designs and data, but has not confirmed whether the binders neutralize venom in cells and does not claim to have produced an antivenom.


推荐理由:实验测试已有 17 个方案符合结合标准,且全部 211 个设计及数据已公开;能否中和蝎毒仍是关键的未验证环节。